The directory contains supplementary material to paper:

"Automated high-throughput registration for localizing 
3D mouse brain gene expression using ITK", 
Ng, Hawrylycz and Haynor

submitted to:
"Open-Source Workshop at the 2005 MICCAI"

This directory contains two new classes:
  itkCombinedImageToImageMetricAdaptor
  itkMeanSquaresImageToImageMetric2

-----------------------------------
The itkCombinedImageToImageMetricAdaptor implements a registration
metric which is a weighted sum of a vector of underlying metrics.

The use of this class is illustrated in ImageRegistration3-mod.exe
where a weighted mean squares and normalized correlation metric is use
to register two images.

Command line arguments: ImageRegistration3-mod.exe
BrainProtonDensitySliceBorder20.png
BrainProtonDensitySliceShifted13x17y.png ImageRegistration3-mod.png

-----------------------------------
The itkMeanSquaresImageToImageMetric is a modification of the the
original mean squares metric. This class has be optimized when used in
registration with a BSplineDeformableTransform class by only updating
the derivatives of parameters that are within the BSpline support of
each sample pixel.

The use of this class is illustrated in
DeformableRegistration6-mod.exe.

Command line arguments: DeformableRegistration6-mod.exe
BrainProtonDensitySliceBorder20.png
BrainProtonDensitySliceBSplined10.png DeformableRegistration6-mod.png

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Note: Code in directory has only been tested on a Windows/ Visual
Studio .NET 2003 environment on cvs checkout July 29, 2005.

-----------------------------------
Lydia Ng
(lydian@alleninstitute.org)